AAPK-25, CAS [[2247919-28-2]]

Produktübersicht

• Artikelname: AAPK-25, CAS [[2247919-28-2]]
• Artikelnummer: MCE-HY-126249
• Hersteller Artikelnummer: HY-126249
• Alternativnummer: MCE-HY-126249-100MG,MCE-HY-126249-10MMX1ML,MCE-HY-126249-5MG,MCE-HY-126249-10MG,MCE-HY-126249-25MG,MCE-HY-126249-50MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

AAPK-25 is a potent and selective Aurora/PLK dual inhibitor with anti-tumor activity, which can cause mitotic delay and arrest cells in a prometaphase, reflecting by the biomarker histone H3Ser10 phosphorylation and followed by a surge in apoptosis. AAPK-25 targets Aurora-A, -B, and -C with Kd values ranging from 23-289 nM, as well as PLK-1, -2, and -3 with Kd values ranging from 55-456 nM[1].

Produkteigenschaften

• Molekulargewicht: 442.32
• Reinheit: 98.09
• CAS Nummer: [2247919-28-2]
• Formel: C21H13Cl2N3O2S
• Target-Kategorie: Apoptosis,Aurora Kinase,Polo-like Kinase (PLK)

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound