BI-4924 is a lipophilic, highly plasma protein bound selective phosphoglycerate dehydrogenase (PHGDH) inhibitor (IC50=3 nM) with excellent microsomal, as well as hepatocytic stability. Intracellular trapping of BI-4924 disrupts serine biosynthesis with an IC50 of 2200 nM at 72 h[1].
Molekulargewicht:
499.36
Reinheit:
99.55
CAS Nummer:
[2244452-09-1]
Formel:
C21H20Cl2N2O6S
Target-Kategorie:
Phosphoglycerate Dehydrogenase (PHGDH)
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten