BI-4924 is a lipophilic, highly plasma protein bound selective phosphoglycerate dehydrogenase (PHGDH) inhibitor (IC50=3 nM) with excellent microsomal, as well as hepatocytic stability. Intracellular trapping of BI-4924 disrupts serine biosynthesis with an IC50 of 2200 nM at 72 h[1].
Molecular Weight:
499.36
Purity:
99.55
CAS Number:
[2244452-09-1]
Formula:
C21H20Cl2N2O6S
Target:
Phosphoglycerate Dehydrogenase (PHGDH)
Application Notes:
MCE Product type: Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted
