TCMDC-135051 is a highly selective and potent protein kinase PfCLK3 inhibitor with low off-target toxicity. TCMDC-135051 prevents trophozoite-to-schizont transition, disrupts transcription and reduces transmission to the mosquito vector. TCMDC-135051 has antiparasiticidal activity (EC50=320 nM)[1].
Molekulargewicht:
471.59
Reinheit:
99.90
CAS Nummer:
[2413716-15-9]
Formel:
C29H33N3O3
Target-Kategorie:
Parasite
Anwendungsbeschreibung:
Reference compound
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