TCMDC-135051 is a highly selective and potent protein kinase PfCLK3 inhibitor with low off-target toxicity. TCMDC-135051 prevents trophozoite-to-schizont transition, disrupts transcription and reduces transmission to the mosquito vector. TCMDC-135051 has antiparasiticidal activity (EC50=320 nM)[1].
Molecular Weight:
471.59
Purity:
99.90
CAS Number:
[2413716-15-9]
Formula:
C29H33N3O3
Target:
Parasite
Application Notes:
Reference compound
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