NRL-1049 dihydrochloride (BA-1049) is a selective and orally active rho-associated protein kinase 2 (ROCK2) inhibitor with an IC50 of 0.59 µM. NRL-1049 dihydrochloride shows selectivity for ROCK2 is 44 times that of ROCK1 (IC50 = 26 µM). NRL-1049 dihydrochloride can preserve the blood-brain barrier after acute injury[1].
Molekulargewicht:
392.34
Reinheit:
99.20
CAS Nummer:
[1973494-17-5]
Formel:
C16H23Cl2N3O2S
Target-Kategorie:
ROCK
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten