NRL-1049 dihydrochloride (BA-1049) is a selective and orally active rho-associated protein kinase 2 (ROCK2) inhibitor with an IC50 of 0.59 µM. NRL-1049 dihydrochloride shows selectivity for ROCK2 is 44 times that of ROCK1 (IC50 = 26 µM). NRL-1049 dihydrochloride can preserve the blood-brain barrier after acute injury[1].
Molecular Weight:
392.34
Purity:
99.20
CAS Number:
[1973494-17-5]
Formula:
C16H23Cl2N3O2S
Target:
ROCK
Application Notes:
MCE Product type: Reference compound
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