Marcfortine A, CAS [[75731-43-0]] Preis auf Anfrage
Artikelnummer:
MCE-HY-126638
Hersteller Artikelnummer:
HY-126638
Alternativnummer:
MCE-HY-126638-1MG
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
Alternative Synonym:
NSC 324645
Marcfortine A is an indole alkaloid originally isolated from P. roqueforti. It has nematocidal activity against the parasitic nematode H. contortus (LD99=0.06 µg/mL) and inhibits motility of adult worms (EC50=2 µM). Marcfortine A eliminates H. contortus, T. colubriformis, and O. ostertagi from experimentally infected jirds (ED95s=0.33, 0.11, and 2.5 mg/animal, respectively). It dose-dependently inhibits nicotine-induced calcium mobilization in SH-SY5Y and TE-671 cells expressing alpha3 subunit-containing human nicotinic acetylcholine receptors (nAChRs) and muscle-type nAChRs, respectively.
Molekulargewicht:
477.60
CAS Nummer:
[75731-43-0]
Formel:
C28H35N3O4
Target-Kategorie:
Parasite
Anwendungsbeschreibung:
MCE Product type: Reference compound1
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