Marcfortine A, CAS [[75731-43-0]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-126638
Supplier Catalog Number:
HY-126638
Alternative Catalog Number:
MCE-HY-126638-1MG
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Alternative Names:
NSC 324645
Marcfortine A is an indole alkaloid originally isolated from P. roqueforti. It has nematocidal activity against the parasitic nematode H. contortus (LD99=0.06 µg/mL) and inhibits motility of adult worms (EC50=2 µM). Marcfortine A eliminates H. contortus, T. colubriformis, and O. ostertagi from experimentally infected jirds (ED95s=0.33, 0.11, and 2.5 mg/animal, respectively). It dose-dependently inhibits nicotine-induced calcium mobilization in SH-SY5Y and TE-671 cells expressing alpha3 subunit-containing human nicotinic acetylcholine receptors (nAChRs) and muscle-type nAChRs, respectively.
Molecular Weight:
477.60
CAS Number:
[75731-43-0]
Formula:
C28H35N3O4
Target:
Parasite
Application Notes:
MCE Product type: Reference compound1
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