Entrectinib-d8, CAS [[2251773-94-9]]

Produktübersicht

• Artikelname: Entrectinib-d8, CAS [[2251773-94-9]]
• Artikelnummer: MCE-HY-12678S1
• Hersteller Artikelnummer: HY-12678S1
• Alternativnummer: MCE-HY-12678S1-1MG,MCE-HY-12678S1-5MG,MCE-HY-12678S1-10MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: NMS-E628-d8, RXDX-101-d8

Produktbeschreibung

Entrectinib-d8 (NMS-E628-d8, RXDX-101-d8) is a deuterated version of Entrectinib (HY-12678). Entrectinib (NMS-E628) is an orally available, blood-brain barrier permeable, central nervous system active TrkA/B/C, ROS1 and ALK inhibitor with IC50 values of 1, 3, 5, 12 and 12, respectively. 7 nM. Entrectinib induces apoptosis and cycle arrest in cancer cells, has anti-tumor activity, and also alleviates bleomycin-induced pulmonary fibrosis in mice[1][2][3][4].

Produkteigenschaften

• Molekulargewicht: 568.69
• Reinheit: 99.82
• CAS Nummer: [2251773-94-9]
• Formel: C31H26D8F2N6O2
• Target-Kategorie: Anaplastic lymphoma kinase (ALK),Autophagy,Isotope-Labeled Compounds,ROS Kinase,Trk Receptor

Anwendungsbeschreibung

• Anwendungsbeschreibung: Isotope-Labeled Compounds