TR antagonist 2, CAS [[1073179-55-1]]

Produktübersicht

• Artikelname: TR antagonist 2, CAS [[1073179-55-1]]
• Artikelnummer: MCE-HY-127024A
• Hersteller Artikelnummer: HY-127024A
• Alternativnummer: MCE-HY-127024A-50MG,MCE-HY-127024A-25MG,MCE-HY-127024A-10MG,MCE-HY-127024A-5MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

TR antagonist 2 (Compound 10a) is a competitive thyroid hormone receptors (TRalpha/beta) antagonist (IC50=47 nM). TR antagonist 2 competes with triiodothyronine (T3) for binding to the ligand-binding domain of TR to block receptor-coactivator complex formation and inhibit target gene transcription, reducing thyroid hormone-mediated hypermetabolic effects. TR antagonist 2 is promising for research of hyperthyroidism (e.g., Graves disease) and thyrotoxicosis[1].

Produkteigenschaften

• Molekulargewicht: 463.41
• Reinheit: 98.94
• CAS Nummer: [1073179-55-1]
• Formel: C21H20F3N5O4
• Target-Kategorie: Thyroid Hormone Receptor

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound