TR antagonist 2, CAS [[1073179-55-1]]

Product Overview

• Article Name: TR antagonist 2, CAS [[1073179-55-1]]
• Biozol Catalog Number: MCE-HY-127024A
• Supplier Catalog Number: HY-127024A
• Alternative Catalog Number: MCE-HY-127024A-50MG,MCE-HY-127024A-25MG,MCE-HY-127024A-10MG,MCE-HY-127024A-5MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

TR antagonist 2 (Compound 10a) is a competitive thyroid hormone receptors (TRalpha/beta) antagonist (IC50=47 nM). TR antagonist 2 competes with triiodothyronine (T3) for binding to the ligand-binding domain of TR to block receptor-coactivator complex formation and inhibit target gene transcription, reducing thyroid hormone-mediated hypermetabolic effects. TR antagonist 2 is promising for research of hyperthyroidism (e.g., Graves disease) and thyrotoxicosis[1].

Product Properties

• Molecular Weight: 463.41
• Purity: 98.94
• CAS Number: [1073179-55-1]
• Formula: C21H20F3N5O4
• Target: Thyroid Hormone Receptor

Application Notes

• Application Notes: MCE Product type: Reference compound