YHO-13177, CAS [[912287-56-0]]

Produktübersicht

• Artikelname: YHO-13177, CAS [[912287-56-0]]
• Artikelnummer: MCE-HY-12757
• Hersteller Artikelnummer: HY-12757
• Alternativnummer: MCE-HY-12757-10MG,MCE-HY-12757-5MG,MCE-HY-12757-10MMX1ML,MCE-HY-12757-25MG,MCE-HY-12757-100MG,MCE-HY-12757-50MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

YHO-13177, a acrylonitrile derivative, is an orally active, potent and specific inhibitor of breast cancer resistance protein (BCRP) and ABCG2 with an IC50 value of 10 nM. YHO-13177 potentiates the cytotoxicity of SN-38 in HCT116 and A549 cells that express BCRP. YHO-13177 combined with Irinotecan (HY-16562) significantly suppresses the tumor growth in an HCT116/BCRP xenograft model[1][2][3].

Produkteigenschaften

• Molekulargewicht: 370.47
• Reinheit: 99.65
• CAS Nummer: [912287-56-0]
• Formel: C20H22N2O3S
• Target-Kategorie: BCRP

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound