M-89 is a highly potent and specific menin inhibitor, with a Kd of 1.4 nM for binding to menin. M-89 inhibits the menin-mixed lineage leukemia (Menin-MLL) protein-protein interaction and has potential to treat MLL leukemia. M-89 inhibits the cell growth in leukemia cell lines carrying MLL fusion[1].
Molekulargewicht:
657.87
Reinheit:
99.14
CAS Nummer:
[2363165-42-6]
Formel:
C37H47N5O4S
Target-Kategorie:
Epigenetic Reader Domain
Anwendungsbeschreibung:
MCE Product type: Reference compound1
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