M-89 is a highly potent and specific menin inhibitor, with a Kd of 1.4 nM for binding to menin. M-89 inhibits the menin-mixed lineage leukemia (Menin-MLL) protein-protein interaction and has potential to treat MLL leukemia. M-89 inhibits the cell growth in leukemia cell lines carrying MLL fusion[1].
Molecular Weight:
657.87
Purity:
99.14
CAS Number:
[2363165-42-6]
Formula:
C37H47N5O4S
Target:
Epigenetic Reader Domain
Application Notes:
MCE Product type: Reference compound1
* VAT and and shipping costs not included. Errors and price changes excepted