Bohemine is a purine analogue and is a synthetic and selective CDK inhibitor with IC50s of 4.6 µM, 83 µM, and 2.7 µM for Cdk2/cyclin E, Cdk2/cyclin A, and Cdk9/cyclin T1, respectively. Bohemine also inhibits ERK2 with an IC50 of 52 µM and has less inhibitory effect on CDK1, CDK4 and CDK6. Bohemine has a broad spectrum anti-cancer activities[1][2].
Molekulargewicht:
340.42
Reinheit:
98.93
CAS Nummer:
[189232-42-6]
Formel:
C18H24N6O
Target-Kategorie:
CDK,ERK
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
