Bohemine is a purine analogue and is a synthetic and selective CDK inhibitor with IC50s of 4.6 µM, 83 µM, and 2.7 µM for Cdk2/cyclin E, Cdk2/cyclin A, and Cdk9/cyclin T1, respectively. Bohemine also inhibits ERK2 with an IC50 of 52 µM and has less inhibitory effect on CDK1, CDK4 and CDK6. Bohemine has a broad spectrum anti-cancer activities[1][2].
Molecular Weight:
340.42
Purity:
98.93
CAS Number:
[189232-42-6]
Formula:
C18H24N6O
Target:
CDK,ERK
Application Notes:
MCE Product type: Reference compound
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