Tubulysin is a microtubule destabilizer that binds to the beta-tubulin peptide site adjacent to the vinca alkaloid binding site and inhibits tubulin polymerization. Tubulysin induces apoptosis and exhibits antiproliferative activity against a variety of human cancer cells, including multidrug-resistant strains. Tubulysin can be conjugated to antibodies via a disulfide-containing quaternary ammonium linker for ADC synthesis. Tubulysin is applicable to tumor-related research[1][2][3].
Molekulargewicht:
842.10
Reinheit:
99.53
CAS Nummer:
[1943604-24-7]
Formel:
C44H67N5O9S
Target-Kategorie:
ADC Payload,Antibiotic,Microtubule/Tubulin
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
