SKI-178, CAS [[1259484-97-3]]

Produktübersicht

• Artikelname: SKI-178, CAS [[1259484-97-3]]
• Artikelnummer: MCE-HY-12892
• Hersteller Artikelnummer: HY-12892
• Alternativnummer: MCE-HY-12892-10MMX1ML,MCE-HY-12892-25MG,MCE-HY-12892-5MG,MCE-HY-12892-100MG,MCE-HY-12892-10MG,MCE-HY-12892-50MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

SKI-178 is a potent sphingosine kinase-1 (SphK1) and SphK2 inhibitor. SKI-178 is cytotoxic at IC50 concentrations ranging from 1.8 to 0.1 µM in both agent sensitive and multi-agent resistant cancer cell lines (i.e., MTR3, NCI-ADR and HL60/VCR cells). SKI-178 induces apoptosis in a CDK1-dependent manner in human acute myeloid leukemia cell lines[1][2].

Produkteigenschaften

• Molekulargewicht: 394.42
• Reinheit: 99.29
• CAS Nummer: [1259484-97-3]
• Formel: C21H22N4O4
• Target-Kategorie: Apoptosis,SphK

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound