SLR080811 is a guanidine-based selective sphingosine kinase 2 (SphK2) inhibitor with a Ki of 1.3 µM, exhibiting ~10-fold selectivity over SphK1 (Ki = 12 µM). SLR080811 reduces sphingosine 1-phosphate (S1P) levels in vitro, but drives a SphK1-dependent increase in S1P in mice. SLR080811 can be used for cancers and fibrosis research[1].
Molekulargewicht:
369.50
CAS Nummer:
[1449765-65-4]
Formel:
C21H31N5O
Target-Kategorie:
SphK
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
