Aspergillomarasmine A, CAS [[3484-65-9]] Preis auf Anfrage

Produktübersicht

• Artikelname: Aspergillomarasmine A, CAS [[3484-65-9]] Preis auf Anfrage
• Artikelnummer: MCE-HY-129200
• Hersteller Artikelnummer: HY-129200
• Alternativnummer: MCE-HY-129200-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

Aspergillomarasmine A is a natural aminopolycarboxylic acid with potent inhibitory activity against class B metallo-beta-lactamases (MBLs). Aspergillomarasmine A inactivates MBLs by removing a catalytic Zn2+ cofactor. Aspergillomarasmine A acts as a selective Zn2+ scavenger, promoting the dissociation of the metal cofactor, thereby indirectly inactivating NDM-1. Aspergillomarasmine A causes the loss of Zn2+ ions from the low-affinity binding site of NDM-1. The action of Aspergillomarasmine A results in the rapid degradation of Zn2+-deficient NDM-1, thereby enhancing its potency as a beta-lactam enhancer. The mechanism of Aspergillomarasmine A has broad applicability among different Zn2+ chelators[1].

Produkteigenschaften

• Molekulargewicht: 307.26
• CAS Nummer: [3484-65-9]
• Formel: C10H17N3O8
• Target-Kategorie: Endogenous Metabolite

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Natural Products