Aspergillomarasmine A, CAS [[3484-65-9]] Preis auf Anfrage

Product Overview

• Article Name: Aspergillomarasmine A, CAS [[3484-65-9]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-129200
• Supplier Catalog Number: HY-129200
• Alternative Catalog Number: MCE-HY-129200-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

Aspergillomarasmine A is a natural aminopolycarboxylic acid with potent inhibitory activity against class B metallo-beta-lactamases (MBLs). Aspergillomarasmine A inactivates MBLs by removing a catalytic Zn2+ cofactor. Aspergillomarasmine A acts as a selective Zn2+ scavenger, promoting the dissociation of the metal cofactor, thereby indirectly inactivating NDM-1. Aspergillomarasmine A causes the loss of Zn2+ ions from the low-affinity binding site of NDM-1. The action of Aspergillomarasmine A results in the rapid degradation of Zn2+-deficient NDM-1, thereby enhancing its potency as a beta-lactam enhancer. The mechanism of Aspergillomarasmine A has broad applicability among different Zn2+ chelators[1].

Product Properties

• Molecular Weight: 307.26
• CAS Number: [3484-65-9]
• Formula: C10H17N3O8
• Target: Endogenous Metabolite

Application Notes

• Application Notes: MCE Product type: Natural Products