MG-277, CAS [[2411085-89-5]]

Produktübersicht

• Artikelname: MG-277, CAS [[2411085-89-5]]
• Artikelnummer: MCE-HY-130122
• Hersteller Artikelnummer: HY-130122
• Alternativnummer: MCE-HY-130122-5MG,MCE-HY-130122-10MG,MCE-HY-130122-25MG,MCE-HY-130122-1MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

MG-277, a molecular glue degrader, effectively induces degradation of a translation termination factor based on Cereblon E3 ligand, GSPT1, with a DC50 of 1.3 nM. MG-277 potently inhibits tumor cell growth in a p53-independent manner, with IC50s of 3.5 nM for RS4,11 cells and 3.4 nM for p53 mutant RS4,11/IRMI-2 cells, respectively. Anticancer activity[1].

Produkteigenschaften

• Molekulargewicht: 774.71
• Reinheit: 98.68
• CAS Nummer: [2411085-89-5]
• Formel: C41H42Cl2FN5O5
• Target-Kategorie: Apoptosis,Molecular Glues,PROTACs

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound1