LC3-mHTT-IN-AN1 (Compound AN1) is a mHTT-LC3 linker compound, which interacts with both mutant huntingtin protein (mHTT) and LC3B but not with wtHTT or irrelevant control proteins. LC3-mHTT-IN-AN1 reduces the levels of mHTT in an allele-selective manner in cultured Huntington disease (HD) mouse neurons[1].
Molekulargewicht:
411.04
Reinheit:
98.86
CAS Nummer:
[486443-73-6]
Formel:
C15H9Br2NO3
Target-Kategorie:
Atg8/LC3,Autophagy
Anwendungsbeschreibung:
MCE Product type: Reference compound
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