LC3-mHTT-IN-AN1 (Compound AN1) is a mHTT-LC3 linker compound, which interacts with both mutant huntingtin protein (mHTT) and LC3B but not with wtHTT or irrelevant control proteins. LC3-mHTT-IN-AN1 reduces the levels of mHTT in an allele-selective manner in cultured Huntington disease (HD) mouse neurons[1].
Molecular Weight:
411.04
Purity:
98.86
CAS Number:
[486443-73-6]
Formula:
C15H9Br2NO3
Target:
Atg8/LC3,Autophagy
Application Notes:
MCE Product type: Reference compound
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