HDAC/HSP90-IN-1, CAS [[2244714-37-0]] Preis auf Anfrage

Artikelnummer: MCE-HY-130273
Artikelname: HDAC/HSP90-IN-1, CAS [[2244714-37-0]] Preis auf Anfrage
Artikelnummer: MCE-HY-130273
Hersteller Artikelnummer: HY-130273
Alternativnummer: MCE-HY-130273-1UNIT
Hersteller: MedchemExpress
Kategorie: Biochemikalien
HDAC/HSP90-IN-1 (compound 20) is a potent dual inhibitor of HDAC (IC50 = 194 nM) and HSP90 (HSP90alpha IC50 = 153 nM). HDAC/HSP90-IN-1 induces HSP70 expression, downregulates HSP90 client proteins, and promotes acetylation of alpha-tubulin and histone H3 in cancer cells. HDAC/HSP90-IN-1 reduces PD-L1 expression in IFN-gamma treated H1975 cells. HDAC/HSP90-IN-1 can be used for cancer research, such as lung and colon cancer[1].
Molekulargewicht: 471.55
CAS Nummer: [2244714-37-0]
Formel: C25H33N3O6
Target-Kategorie: HDAC,HSP,Microtubule/Tubulin,PD-1/PD-L1
Anwendungsbeschreibung: MCE Product type: Reference compound