HDAC/HSP90-IN-1, CAS [[2244714-37-0]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-130273
Supplier Catalog Number:
HY-130273
Alternative Catalog Number:
MCE-HY-130273-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
HDAC/HSP90-IN-1 (compound 20) is a potent dual inhibitor of HDAC (IC50 = 194 nM) and HSP90 (HSP90alpha IC50 = 153 nM). HDAC/HSP90-IN-1 induces HSP70 expression, downregulates HSP90 client proteins, and promotes acetylation of alpha-tubulin and histone H3 in cancer cells. HDAC/HSP90-IN-1 reduces PD-L1 expression in IFN-gamma treated H1975 cells. HDAC/HSP90-IN-1 can be used for cancer research, such as lung and colon cancer[1].
Molecular Weight:
471.55
CAS Number:
[2244714-37-0]
Formula:
C25H33N3O6
Target:
HDAC,HSP,Microtubule/Tubulin,PD-1/PD-L1
Application Notes:
MCE Product type: Reference compound
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