DT2216, CAS [[2365172-42-3]]

Produktübersicht

• Artikelname: DT2216, CAS [[2365172-42-3]]
• Artikelnummer: MCE-HY-130604
• Hersteller Artikelnummer: HY-130604
• Alternativnummer: MCE-HY-130604-5MG,MCE-HY-130604-25MG,MCE-HY-130604-50MG,MCE-HY-130604-10MG,MCE-HY-130604-100MG,MCE-HY-130604-1MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

DT2216 is a potent and selective BCL-XL (Bcl-2 family member) degrader based on PROTAC technology. DT2216 causes effective degradation of BCL-XL protein by recruiting Von Hippel-Lindau (VHL) E3 ubiquitin ligase. DT2216 inhibits various BCL-XL-dependent leukemia and cancer cells but considerably less toxic to platelets. DT2216 is composed of the Bcl-2 family protein inhibitor Navitoclax-piperazine (HY-44432), a linker, and a VHL E3 ubiquitin ligase (Pink: Navitoclax-piperazine, Blue: VHL ligand, Black: linker)[1].

Produkteigenschaften

• Molekulargewicht: 1542.36
• Reinheit: 99.97
• CAS Nummer: [2365172-42-3]
• Formel: C77H96ClF3N10O10S4
• Target-Kategorie: Apoptosis,Bcl-2 Family,PROTACs

Anwendungsbeschreibung

• Anwendungsbeschreibung: Reference compound