BMS-1166-N-piperidine-COOH, CAS [[2447066-00-2]]

Produktübersicht

• Artikelname: BMS-1166-N-piperidine-COOH, CAS [[2447066-00-2]]
• Artikelnummer: MCE-HY-131187
• Hersteller Artikelnummer: HY-131187
• Alternativnummer: MCE-HY-131187-10MMX1ML,MCE-HY-131187-100MG,MCE-HY-131187-50MG,MCE-HY-131187-25MG,MCE-HY-131187-10MG,MCE-HY-131187-5MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

BMS-1166-N-piperidine-COOH, the BMS-1166-based moiety, binds to E3 ligase ligand via a linker to form PROTAC PD-1/PD-L1 degrader-1 (HY-131183) to degrade PD-1/PD-L1[1]. BMS-1166 is a potent PD-1/PD-L1 interaction inhibitor with an IC50 of 1.4 nM. BMS-1166 antagonizes the inhibitory effect of PD-1/PD-L1 immune checkpoint on T cell activation[2].

Produkteigenschaften

• Molekulargewicht: 639.14
• Reinheit: 97.18
• CAS Nummer: [2447066-00-2]
• Formel: C37H35ClN2O6
• Target-Kategorie: Ligands for Target Protein for PROTAC

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound1