FNDR-20123 (free base), CAS [[1267502-34-0]] Preis auf Anfrage

Produktübersicht

• Artikelname: FNDR-20123 (free base), CAS [[1267502-34-0]] Preis auf Anfrage
• Artikelnummer: MCE-HY-131708
• Hersteller Artikelnummer: HY-131708
• Alternativnummer: MCE-HY-131708-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

FNDR-20123 free base is a safe, first-in-class, and orally active anti-malarial HDAC inhibitor with IC50s of 31 nM and 3 nM for Plasmodium and human HDAC, respectively. FNDR-20123 free base exerts anti-malarial activity against Plasmodium falciparum asexual stage (IC50=41 nM) and sexual blood stage (IC50=190 nM for male gametocytes). FNDR-20123 free base inhibits HDAC1, HDAC2, HDAC3, HDAC6, and HDAC8 (IC50=25, 29, 2, 11, and 282 nM, respectively) and inhibits Class III HDAC isoforms at nanomolar concentrations[1].

Produkteigenschaften

• Molekulargewicht: 377.44
• CAS Nummer: [1267502-34-0]
• Formel: C21H23N5O2
• Target-Kategorie: HDAC,Parasite

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound