FNDR-20123 (free base), CAS [[1267502-34-0]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-131708
Supplier Catalog Number:
HY-131708
Alternative Catalog Number:
MCE-HY-131708-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
FNDR-20123 free base is a safe, first-in-class, and orally active anti-malarial HDAC inhibitor with IC50s of 31 nM and 3 nM for Plasmodium and human HDAC, respectively. FNDR-20123 free base exerts anti-malarial activity against Plasmodium falciparum asexual stage (IC50=41 nM) and sexual blood stage (IC50=190 nM for male gametocytes). FNDR-20123 free base inhibits HDAC1, HDAC2, HDAC3, HDAC6, and HDAC8 (IC50=25, 29, 2, 11, and 282 nM, respectively) and inhibits Class III HDAC isoforms at nanomolar concentrations[1].
Molecular Weight:
377.44
CAS Number:
[1267502-34-0]
Formula:
C21H23N5O2
Target:
HDAC,Parasite
Application Notes:
MCE Product type: Reference compound1
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