CCT128930 (hydrochloride), CAS [[2453324-32-6]]

Produktübersicht

• Artikelname: CCT128930 (hydrochloride), CAS [[2453324-32-6]]
• Artikelnummer: MCE-HY-13260A
• Hersteller Artikelnummer: HY-13260A
• Alternativnummer: MCE-HY-13260A-10MG,MCE-HY-13260A-5MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

CCT128930 hydrochloride is a potent and selective inhibitor of AKT (IC50=6 nM). CCT128930 hydrochloride has 28-fold selectivity over the closely related PKA kinase (IC50=168 nM) through the targeting of Met282 of AKT (Met173 of PKA-AKT chimera), as well as 20-fold selectivity over p70S6K (IC50=120 nM). CCT128930 hydrochloride induces cell cycle arrest, DNA damage, and autophagy. Antitumor activity[1][2].

Produkteigenschaften

• Molekulargewicht: 378.30
• Reinheit: 98.97
• CAS Nummer: [2453324-32-6]
• Formel: C18H21Cl2N5
• Target-Kategorie: Akt,Apoptosis,Autophagy

Anwendungsbeschreibung

• Anwendungsbeschreibung: Reference compound