ABT-751 (hydrochloride), CAS [[141450-48-8]] Preis auf Anfrage

Produktübersicht

• Artikelname: ABT-751 (hydrochloride), CAS [[141450-48-8]] Preis auf Anfrage
• Artikelnummer: MCE-HY-13270A
• Hersteller Artikelnummer: HY-13270A
• Alternativnummer: MCE-HY-13270A-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: E7010 (hydrochloride)

Produktbeschreibung

ABT-751 (E7010) hydrochloride is a novel, highly orally bioavailable sulfonamides antimitotic compound and tubulin binder. It prevents tubulin aggregation by binding to the colchicine site on beta-tubulin, leading to cell cycle arrest in G2/M phase and inducing apoptosis, thus effectively preventing cell division. ABT-751 (E7010) hydrochloride induces autophagy by inhibiting the AKT/MTOR signaling pathway. ABT-751 (E7010) hydrochloride showed significant inhibition against various types of cancer cells, including lung, gastric, colon, and breast cancer[1][2][3][4][5][6][7][8][9].

Produkteigenschaften

• Molekulargewicht: 407.87
• CAS Nummer: [141450-48-8]
• Formel: C18H18ClN3O4S
• Target-Kategorie: Apoptosis,Autophagy,Microtubule/Tubulin

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound