ABT-751 (hydrochloride), CAS [[141450-48-8]] Preis auf Anfrage

Product Overview

• Article Name: ABT-751 (hydrochloride), CAS [[141450-48-8]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-13270A
• Supplier Catalog Number: HY-13270A
• Alternative Catalog Number: MCE-HY-13270A-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: E7010 (hydrochloride)

Product Description

ABT-751 (E7010) hydrochloride is a novel, highly orally bioavailable sulfonamides antimitotic compound and tubulin binder. It prevents tubulin aggregation by binding to the colchicine site on beta-tubulin, leading to cell cycle arrest in G2/M phase and inducing apoptosis, thus effectively preventing cell division. ABT-751 (E7010) hydrochloride induces autophagy by inhibiting the AKT/MTOR signaling pathway. ABT-751 (E7010) hydrochloride showed significant inhibition against various types of cancer cells, including lung, gastric, colon, and breast cancer[1][2][3][4][5][6][7][8][9].

Product Properties

• Molecular Weight: 407.87
• CAS Number: [141450-48-8]
• Formula: C18H18ClN3O4S
• Target: Apoptosis,Autophagy,Microtubule/Tubulin

Application Notes

• Application Notes: MCE Product type: Reference compound