Aminoflavone, CAS [[165179-35-1]] Preis auf Anfrage

Produktübersicht

• Artikelname: Aminoflavone, CAS [[165179-35-1]] Preis auf Anfrage
• Artikelnummer: MCE-HY-132974
• Hersteller Artikelnummer: HY-132974
• Alternativnummer: MCE-HY-132974-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: NSC-686288

Produktbeschreibung

Aminoflavone is an anti-tumor agent. Aminoflavone inhibits the expression of ITGA6/SOX2 by activating the AhR-miR-125b-2-3p axis, thereby targeting breast cancer stem cells. Aminoflavone induces an increase in intracellular ROS, increases the level of oxidative DNA damage marker 8-oxodG and DNA-protein cross-links. Aminoflavone causes S-phase arrest, activates caspase-3/8/9 and induces apoptosis (apoptosis). Aminoflavone inhibits HIF-1alpha expression in a manner independent of AhR. Aminoflavone can be used for the study of breast cancer[1][2][3].

Produkteigenschaften

• Molekulargewicht: 320.27
• CAS Nummer: [165179-35-1]
• Formel: C16H11F3N2O2
• Target-Kategorie: Apoptosis,Aryl Hydrocarbon Receptor,Caspase,DNA Alkylator/Crosslinker,DNA/RNA Synthesis,HIF/HIF Prolyl-Hydroxylase,Reactive Oxygen Species (ROS)

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound