Aminoflavone, CAS [[165179-35-1]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-132974
Supplier Catalog Number:
HY-132974
Alternative Catalog Number:
MCE-HY-132974-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Alternative Names:
NSC-686288
Aminoflavone is an anti-tumor agent. Aminoflavone inhibits the expression of ITGA6/SOX2 by activating the AhR-miR-125b-2-3p axis, thereby targeting breast cancer stem cells. Aminoflavone induces an increase in intracellular ROS, increases the level of oxidative DNA damage marker 8-oxodG and DNA-protein cross-links. Aminoflavone causes S-phase arrest, activates caspase-3/8/9 and induces apoptosis (apoptosis). Aminoflavone inhibits HIF-1alpha expression in a manner independent of AhR. Aminoflavone can be used for the study of breast cancer[1][2][3].
Molecular Weight:
320.27
CAS Number:
[165179-35-1]
Formula:
C16H11F3N2O2
Target:
Apoptosis,Aryl Hydrocarbon Receptor,Caspase,DNA Alkylator/Crosslinker,DNA/RNA Synthesis,HIF/HIF Prolyl-Hydroxylase,Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Reference compound
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