Boc-Pip-alkyne-Ph-COOH, CAS [[2581824-70-4]] Preis auf Anfrage

Produktübersicht

• Artikelname: Boc-Pip-alkyne-Ph-COOH, CAS [[2581824-70-4]] Preis auf Anfrage
• Artikelnummer: MCE-HY-133044
• Hersteller Artikelnummer: HY-133044
• Alternativnummer: MCE-HY-133044-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

Boc-Pip-alkyne-Ph-COOH is a PROTAC linker, which refers to the alkyl/ether composition. Boc-Pip-alkyne-Ph-COOH can be used in the synthesis of a series of PROTACs, such as ARD-266 (HY-133020). ARD-266 effectively induces degradation of androgen receptor (AR) protein in AR-positive LNCaP, VCaP, and 22Rv1 prostate cancer cell lines with DC50 values of 0.2-1 nM[1]. Boc-Pip-alkyne-Ph-COOH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Produkteigenschaften

• Molekulargewicht: 329.39
• CAS Nummer: [2581824-70-4]
• Formel: C19H23NO4
• Target-Kategorie: PROTAC Linkers

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound