Boc-Pip-alkyne-Ph-COOH, CAS [[2581824-70-4]] Preis auf Anfrage

Product Overview

• Article Name: Boc-Pip-alkyne-Ph-COOH, CAS [[2581824-70-4]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-133044
• Supplier Catalog Number: HY-133044
• Alternative Catalog Number: MCE-HY-133044-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

Boc-Pip-alkyne-Ph-COOH is a PROTAC linker, which refers to the alkyl/ether composition. Boc-Pip-alkyne-Ph-COOH can be used in the synthesis of a series of PROTACs, such as ARD-266 (HY-133020). ARD-266 effectively induces degradation of androgen receptor (AR) protein in AR-positive LNCaP, VCaP, and 22Rv1 prostate cancer cell lines with DC50 values of 0.2-1 nM[1]. Boc-Pip-alkyne-Ph-COOH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Product Properties

• Molecular Weight: 329.39
• CAS Number: [2581824-70-4]
• Formula: C19H23NO4
• Target: PROTAC Linkers

Application Notes

• Application Notes: MCE Product type: Reference compound