Apatinib-d8 (free base), CAS [[2468771-43-7]]

Produktübersicht

• Artikelname: Apatinib-d8 (free base), CAS [[2468771-43-7]]
• Artikelnummer: MCE-HY-13342AS
• Hersteller Artikelnummer: HY-13342AS
• Alternativnummer: MCE-HY-13342AS-1MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: YN968D1-d8 (free base)

Produktbeschreibung

Apatinib-d8 (free base) is the deuterium labeled Apatinib free base[1]. Apatinib free base (YN968D1 free base) is an orally bioavailable tyrosine kinase inhibitor, which selectively targets VEGFR-2 (IC50=1 nM). Apatinib free base (YN968D1 free base) is an anti-angiogenic drug for the research of advanced or metastatic gastric cancer. Apatinib free base (YN968D1 free base) potently inhibits Ret, c-Kit and c-Src with IC50s of 13, 429 and 530 nM, respectively. It also inhibits cellular phosphorylation of VEGFR-2, c-kit and PDGFRbeta[2][3][4].

Produkteigenschaften

• Molekulargewicht: 405.52
• Reinheit: 92.56
• CAS Nummer: [2468771-43-7]
• Formel: C24H15D8N5O
• Target-Kategorie: Autophagy,c-Kit,RET,Src,VEGFR

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Isotope-Labeled Compounds