5,6-Dihydro-5-Fluorouracil, CAS [[696-06-0]]

Produktübersicht

• Artikelname: 5,6-Dihydro-5-Fluorouracil, CAS [[696-06-0]]
• Artikelnummer: MCE-HY-134160
• Hersteller Artikelnummer: HY-134160
• Alternativnummer: MCE-HY-134160-10MG,MCE-HY-134160-1MG,MCE-HY-134160-5MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: 5-DHFU, 5-Fluorodihydropyrimidine-2,4-dione, 5-Fluorodihydrouracil

Produktbeschreibung

5,6-Dihydro-5-Fluorouracil (5-DHFU, 5-Fluorodihydropyrimidine-2,4-dione) is the active metabolite of the thymidylate synthase inhibitor prodrug 5-fluorouracil (HY-90006), which is formed from 5-fluorouracil by dihydropyrimidine dehydrogenase (DPD). 5,6-Dihydro-5-Fluorouracil is cytotoxic to HaCaT keratinocytes (IC50=13.5 µM). Intravenous administration of 5,6-Dihydro-5-Fluorouracil (90 mg/kg/wk) in combination with 5-fluorouracil and the DPD inhibitor eniluracil (HY-10533) slows tumor growth in a rat colon cancer model.

Produkteigenschaften

• Molekulargewicht: 132.09
• Reinheit: 99.90
• CAS Nummer: [696-06-0]
• Formel: C4H5FN2O2
• Target-Kategorie: Nucleoside Antimetabolite/Analog

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound