KW-2478 (hydrochloride), CAS [[819812-18-5]] Preis auf Anfrage

Artikelnummer: MCE-HY-13468A
Artikelname: KW-2478 (hydrochloride), CAS [[819812-18-5]] Preis auf Anfrage
Artikelnummer: MCE-HY-13468A
Hersteller Artikelnummer: HY-13468A
Alternativnummer: MCE-HY-13468A-1UNIT
Hersteller: MedchemExpress
Kategorie: Biochemikalien
KW-2478 hydrochloride is an HSP90 inhibitor (IC50 = 3.8 nM). KW-2478 hydrochloride inhibits the growth and induces apoptosis in chronic myeloid leukemia (CML) cells and liver cancer cells. KW-2478 hydrochloride weakens the BCR/ABL and MAPK signaling pathways, leading to increased p27 and p21 expression and decreased cyclin B1 expression. KW-2478 hydrochloride downregulates STAT3 expression. KW-2478 hydrochloride may be used in research on cancers such as CML and liver cancer[1][2].
Molekulargewicht: 611.12
CAS Nummer: [819812-18-5]
Formel: C30H43ClN2O9
Target-Kategorie: Apoptosis,Bcr-Abl,CDK,HSP,p38 MAPK,STAT
Anwendungsbeschreibung: MCE Product type: Reference compound