AS1940477 (Compound 3f) is an orally active p38 MAPK inhibitor. AS1940477 inhibits the enzymatic activity of recombinant p38alpha and beta isoforms. AS1940477 inhibits the production of pro-inflammatory cytokines (including TNFalpha, IL-1beta, and IL-6) in human synovial interstitial cells and animal models of inflammation. AS1940477 can be used in research on inflammatory diseases[1][2].
Molekulargewicht:
431.46
CAS Nummer:
[928344-12-1]
Formel:
C24H22FN5O2
Target-Kategorie:
Interleukin Related,p38 MAPK,TNF Receptor
Anwendungsbeschreibung:
MCE Product type: Reference compound1
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
