AS1940477 (Compound 3f) is an orally active p38 MAPK inhibitor. AS1940477 inhibits the enzymatic activity of recombinant p38alpha and beta isoforms. AS1940477 inhibits the production of pro-inflammatory cytokines (including TNFalpha, IL-1beta, and IL-6) in human synovial interstitial cells and animal models of inflammation. AS1940477 can be used in research on inflammatory diseases[1][2].
Molecular Weight:
431.46
CAS Number:
[928344-12-1]
Formula:
C24H22FN5O2
Target:
Interleukin Related,p38 MAPK,TNF Receptor
Application Notes:
MCE Product type: Reference compound1
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