SBI-0087702 promots the cytoplasmic localization of ATF2 in melanoma cells. SBI-0087702-induced translocation of ATF2 to the mitochondria results in increased apoptosis due to loss of mitochondrial membrane integrity. SBI-0087702 also inhibits growth and motility of melanoma cells. SBI-0087702 was shown to inhibit ATF2 phosphorylation on Thr52 by PKCepsilon[1].
Molekulargewicht:
321.41
Reinheit:
99.55
CAS Nummer:
[864431-36-7]
Formel:
C21H23NO2
Target-Kategorie:
PKC
Anwendungsbeschreibung:
MCE Product type: Reference compound
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