Emavusertib (maleate), CAS [[2376399-39-0]] Preis auf Anfrage

Produktübersicht

• Artikelname: Emavusertib (maleate), CAS [[2376399-39-0]] Preis auf Anfrage
• Artikelnummer: MCE-HY-135317E
• Hersteller Artikelnummer: HY-135317E
• Alternativnummer: MCE-HY-135317E-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: CA-4948 (maleate)

Produktbeschreibung

Emavusertib maleate (CA-4948 maleate) is the maleate salt form of Emavusertib (HY-135317). Emavusertib maleate is an orally active inhibitor for IRAK4 (IC50=57 nM) and FLT3. Emavusertib maleate inhibits NF-kappaB and MyD88 signaling pathways, reduces the generation of pro-inflammatory cytokines like IL-6 and IL-10, thereby exhibiting anti-inflammatory and anti-proliferative activities against cancer cells, leading to cell apoptosis. Emavusertib maleate exhibits antitumor activity in mouse model[1][2][3].

Produkteigenschaften

• Molekulargewicht: 607.57
• CAS Nummer: [2376399-39-0]
• Formel: C28H29N7O9
• Target-Kategorie: Apoptosis,FLT3,IRAK,MyD88,NF-kappaB

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound