Emavusertib (maleate), CAS [[2376399-39-0]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-135317E
Supplier Catalog Number:
HY-135317E
Alternative Catalog Number:
MCE-HY-135317E-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Alternative Names:
CA-4948 (maleate)
Emavusertib maleate (CA-4948 maleate) is the maleate salt form of Emavusertib (HY-135317). Emavusertib maleate is an orally active inhibitor for IRAK4 (IC50=57 nM) and FLT3. Emavusertib maleate inhibits NF-kappaB and MyD88 signaling pathways, reduces the generation of pro-inflammatory cytokines like IL-6 and IL-10, thereby exhibiting anti-inflammatory and anti-proliferative activities against cancer cells, leading to cell apoptosis. Emavusertib maleate exhibits antitumor activity in mouse model[1][2][3].
Molecular Weight:
607.57
CAS Number:
[2376399-39-0]
Formula:
C28H29N7O9
Target:
Apoptosis,FLT3,IRAK,MyD88,NF-kappaB
Application Notes:
MCE Product type: Reference compound
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