SJF-0628, CAS [[2413035-41-1]]

Produktübersicht

• Artikelname: SJF-0628, CAS [[2413035-41-1]]
• Artikelnummer: MCE-HY-136420
• Hersteller Artikelnummer: HY-136420
• Alternativnummer: MCE-HY-136420-5MG,MCE-HY-136420-10MG,MCE-HY-136420-1MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

SJF-0628 is a RAF PROTAC degrader. SJF-0628 induces targeted degradation of BRAF in various cancer cell lines (colorectal cancer cell lines (Colo-205, LS-411N, HT-29, RKO) and triple-negative breast cancer cell line DU-4475). SJF-0628 decreases pMEK and pErk levels in DU-4475 cells. SJF-0628 has anti-tumor activity. SJF-0628 can be used for research of colorectal cancer and triple-negative breast cancer. (Pink: RAF ligand (HY-12057), Blue: VHL Ligand ( HY-125845), Black: Linker (HY-B0912))[1].

Produkteigenschaften

• Molekulargewicht: 1010.18
• Reinheit: 99.90
• CAS Nummer: [2413035-41-1]
• Formel: C51H57F2N9O7S2
• Target-Kategorie: Apoptosis,PROTACs,Raf

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound