SJF-0628, CAS [[2413035-41-1]]

Product Overview

• Article Name: SJF-0628, CAS [[2413035-41-1]]
• Biozol Catalog Number: MCE-HY-136420
• Supplier Catalog Number: HY-136420
• Alternative Catalog Number: MCE-HY-136420-5MG,MCE-HY-136420-10MG,MCE-HY-136420-1MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

SJF-0628 is a RAF PROTAC degrader. SJF-0628 induces targeted degradation of BRAF in various cancer cell lines (colorectal cancer cell lines (Colo-205, LS-411N, HT-29, RKO) and triple-negative breast cancer cell line DU-4475). SJF-0628 decreases pMEK and pErk levels in DU-4475 cells. SJF-0628 has anti-tumor activity. SJF-0628 can be used for research of colorectal cancer and triple-negative breast cancer. (Pink: RAF ligand (HY-12057), Blue: VHL Ligand ( HY-125845), Black: Linker (HY-B0912))[1].

Product Properties

• Molecular Weight: 1010.18
• Purity: 99.90
• CAS Number: [2413035-41-1]
• Formula: C51H57F2N9O7S2
• Target: Apoptosis,PROTACs,Raf

Application Notes

• Application Notes: MCE Product type: Reference compound