Kv1.5-IN-1, CAS [[1469902-72-4]] Preis auf Anfrage

Produktübersicht

• Artikelname: Kv1.5-IN-1, CAS [[1469902-72-4]] Preis auf Anfrage
• Artikelnummer: MCE-HY-136805
• Hersteller Artikelnummer: HY-136805
• Alternativnummer: MCE-HY-136805-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

Kv1.5-IN-1 is a Kv1.5 channel inhibitor. Its target selectivity and pharmacodynamic effects were evaluated in an in vitro rat model. After the introduction of a methoxy group at the R5 position, Kv1.5-IN-1 showed inhibitory potency similar to that of the unsubstituted compound. Its IC50 value for hKv1.5 channels was 0.51 µM. Kv1.5-IN-1 exhibited a high degree of selectivity, nearly 2,600 times higher than compound Ik and 300 times higher than compound IId, indicating that it may be a safe inhibitor. Due to its good pharmacological behavior, Kv1.5-IN-1 deserves further pharmacodynamic and pharmacokinetic evaluation. These properties make Kv1.5-IN-1 a potential Kv1.5 channel inhibitor that may have application prospects in the treatment of related diseases.

Produkteigenschaften

• Molekulargewicht: 510.99
• CAS Nummer: [1469902-72-4]
• Formel: C25H23ClN4O4S
• Target-Kategorie: Potassium Channel

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound