Kv1.5-IN-1, CAS [[1469902-72-4]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-136805
Supplier Catalog Number:
HY-136805
Alternative Catalog Number:
MCE-HY-136805-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Kv1.5-IN-1 is a Kv1.5 channel inhibitor. Its target selectivity and pharmacodynamic effects were evaluated in an in vitro rat model. After the introduction of a methoxy group at the R5 position, Kv1.5-IN-1 showed inhibitory potency similar to that of the unsubstituted compound. Its IC50 value for hKv1.5 channels was 0.51 µM. Kv1.5-IN-1 exhibited a high degree of selectivity, nearly 2,600 times higher than compound Ik and 300 times higher than compound IId, indicating that it may be a safe inhibitor. Due to its good pharmacological behavior, Kv1.5-IN-1 deserves further pharmacodynamic and pharmacokinetic evaluation. These properties make Kv1.5-IN-1 a potential Kv1.5 channel inhibitor that may have application prospects in the treatment of related diseases.
Molecular Weight:
510.99
CAS Number:
[1469902-72-4]
Formula:
C25H23ClN4O4S
Target:
Potassium Channel
Application Notes:
MCE Product type: Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted
